The original CFIR (Laura J. Damschroder et al. 2009) provided a broad description of the role of Structural Characteristics. Much support for the role of structural characteristics comes from Damanpour’s seminal research into organizational innovation (Damanpour 1991). Several dimensions of structural characteristics have been found to have significant associations with implementation, though many of these characteristics have had mixed effects, most likely because they interact with other features of the Inner Setting (Frambach and Schillewaert 2001).